This act establishes the Office of Missing and Murdered African American Women and Girls and the Phoenix Alert system. The Phoenix Alert System is designed to help identify and locate abducted or missing African American women and girls who are reasonably believed to be a victim of a criminal offense. This act tasks the Department of Public Safety with developing regions for the system and requires the Office of Missing and Murdered African American Women and Girls to coordinate with local law enforcement to notify local media in the region. Any local law enforcement agency that opts out of establishing a system shall still be responsible for notifying the Office of reports within that agency's jurisdiction. This act requires the system to include at least the Department of Public Safety, the Office of Missing and Murdered African American Women and Girls, the Department of Transportation, the Department of Health and Senior Services, and the Missouri Lottery. Under this act, any person who knowingly makes a false report that triggers an Phoenix Alert shall be guilty of a class A misdemeanor.